Part 63

Although a full list of the tumors that may be found in bovines has been given above, there are a number that warrant a detailed description, and the following mention will be made of the most important of them:

MYOMA.

These tumors are after the type of muscle. They are sharply circumscribed and, as a rule, are very hard, a condition owing usually to combination with fibroma and are then known as fibromyoma. In fact, the clinical differentiation between myoma and fibroma is almost impossible. Myomas are found in the uterus, vagina, stomach, intestines, gullet, and bladder of a bovine animal. They grow very large, but, as a rule, are benign. Treatment should consist of their removal.

NEUROFIBROMA.

A true neuroma built up of nerve fibers and nerve cells is infrequent, if it ever occurs, in cattle. False neuromas, or neurofibromas, are knotty, spreading tumors of the size of a large potato, which are developed within the nerve sheaths and composed of nerve fibers and connective tissue bands interlaced. The commingling of these varied fibers is often so intricate that separation is practically impossible. This tumor is most frequently found upon the shoulder of cattle. Treatment is surgical.

ANGIOMA.

The angiomas are tumors composed mainly of blood vessels or blood spaces and are observed on the skin of man, where they are called "birthmarks" or "mother marks." Cavernous angiomas are seen in cattle, affecting the liver and the mucous membrane of the nasal septum. In the liver they appear as smooth, flat, nonprojecting tumors of a dark-red or purple color and of about the size of a silver 10-cent piece. They are somewhat softer in consistency than the adjoining liver substance into which they are gradually fused. These tumors are frequently observed by meat inspectors in livers of slaughtered cattle. Treatment of angioma is unnecessary.

ADENOMA.

The structure of this tumor is after the type of gland tissue. It is rarely seen in cattle except in combination with cancer or sarcoma. A growth which occurs more frequently in bovines, especially calves, and which in some instances bears a striking resemblance to an adenoma is the so-called goiter.

GOITER (STRUMA).

This is a noninflammatory enlargement or a hyperplasia of the thyroid gland. While it can not be definitely classed among tumors, yet, owing to its resemblance to the latter, it will be discussed at this time. The cause of goiter has never been definitely ascertained. Among the most probable causes may be mentioned heredity, insufficient and improper diet, close confinement, unhygienic surroundings, and an unknown toxic substance which is supposed to obtain in those localities rich in magnesium and lime salts. Certain organisms found in goiter have been suspected of producing this trouble, but their relation to the disease has not been satisfactorily proved. A goiter may consist of (1) simple enlargement of the follicles which are filled with albuminous matter (follicular goiter); (2) an increase of connective tissues between the follicles, causing the swelling to be dense and resistant (fibrous goiter); (3) a great increase in size of one or more follicles, forming a cyst (cystic goiter); (4) great dilatation of the blood vessels in the gland accompanied with pulsation with each heart beat (vascular goiter).

Symptoms.--Goiter may be observed at the side of the throat, reaching the size of a fist or even larger, or it may hang down below the windpipe. In cattle the two thyroid glands are close together, and when the disease affects both there may be but one uniform swelling placed in front of the windpipe below the angle of the jaw. This swelling may be hard, soft, or doughy in consistence, and with each beat of the heart it may pulsate like an artery. It may cause labored breathing by pressure on the windpipe, and death may result from pressure on this structure, on the gullet, or on the adjoining large vessels.

Treatment.--In young animals the treatment is usually satisfactory, and consists in giving the animal a complete change of feed and plenty of exercise in the open air. If the condition appears enzootic in the district, remove the animal to another location when possible. Iodin, either in the form of ointment or the tincture, should be applied to the swelling. Injections of iodin solution, 5 grains of iodin in 1 dram of 25 per cent alcohol, may also be made into the substance of the gland. When the swelling which follows this injection has subsided it may be repeated. Potassium iodid should be given internally in 1-1/2 dram doses twice daily for a cow, or in 20-grain doses twice a day for a calf. Extirpation of all but a small section of the swelling may be successfully accomplished by a qualified veterinarian, but if it should be entirely removed, myxedema and death follow.

FIBROMA.

Fibromas are tumors made up chiefly of connective tissue and are usually confined to the skin and subcutaneous tissue. Indurative fibromas of the skin appear as tumors of gelatinous connective tissue or as firm, white vascular connective tissue growths, which are more or less sharply outlined, move readily over the underlying tissues in company with the skin, and owe their origin to mechanical injuries, perforating wounds, repeated abrasions, or the invasion of pus cocci or botryomyces into the tissues.

These tumors in cattle are frequently found upon the dewlap as solid lumps, hard as stone to the touch, lying loosely between the layers of skin, and gradually losing themselves in the softer tissues of the neck above, or as smooth, hard tumors of glistening white substance with interlacing lines of softer tissue. They may also be found in the region of the knee or at the elbow. The skin over the growths, in accordance with the originating cause, will be found chafed, covered with scabs, or even ulcerated and accompanied with collateral edema.

These connective tissue tumors grow slowly but reach enormous size. They sometimes follow injuries to the region of the throat and form there as hard, firm growth, even reaching the size of a child's head.

A fibroma upon the larynx is not an infrequent occurrence in the ox. These tumors are always sharply outlined and have a roughened surface. They may be differentiated from actinomycotic tumors (see chapter on "Infectious diseases of cattle," p. 358) in the same location by their firm, fibrous structure and by the absence of pus from the interior.

A tumor is sometimes seen upon the muzzle of cattle, which assumes a diameter equaling the width of the muzzle. It is a voluminous connective-tissue formation known by the name of "fibroma diffusum."

Another form is sometimes observed upon the tongue. It grows upon a broad, spreading base, becoming very hard. It is almost lacking in blood vessels, although the few that are present are plainly in view, and in consequence is poorly supplied with fluids. It is of a smooth contour, white or whitish yellow in color, is sharply limited from the normal substance of the tongue, may be covered with mucous membrane, on which prominent papillÊ are located, or only by a thin, delicate layer of epithelium, and is usually found in the middle part of the tongue, where it may reach the size of two fists.

Pedunculate or stemmed fibrous tumors are frequently noticed growing upon or near the extremity of the tails of cows. They are apparently of traumatic origin, such as tying the tail fast while milking or shaving it too closely while trimming for show purposes, and usually contain bloody or gelatinous material within, or, again, they may be strongly edematous throughout.

Treatment.--The treatment of large fibromas is surgical and consists of the operative removal of the tumor, followed by suturing of the wound. Small external tumors may be painted with zinc chlorid, chromic acid, or a concentrated solution of bichlorid of mercury.

PAPILLOMA (WART).

When fibromas develop from the lining or covering tissues they frequently form papillary growths, more or less thickly covered with epithelium, and are then called papillomas, or warts.

Papillomas consist of villouslike projections, resulting from a proliferation of the outer layer (epithelium) of the skin or mucous membrane. These growths are also called "angle berries," and may assume a variety of forms. Sometimes there is a preponderance of epidermis in the formation, and the tumor then appears as a hard, dense, insensitive, clublike growth, or wart. Again the swelling is chiefly in the derm, or true skin, and we have what is known as a flesh wart (verucca carnea). In other cases the growth of papillar bodies projects in great cauliflowerlike tumors with deeply furrowed and lobulated surface, over which a covering of epidermis may or may not be present. These are usually much softer and are well supplied with blood vessels. It is not uncommon for them to be pedunculate or stemmed, and in this case considerable rotary motion or twisting is possible. Their color is cloudy gray or grayish red, with white bands of connective tissue radiating from the center. Their consistence varies. Upon their surfaces and within their clefts and fissures they undergo retrogressive changes, softening, bleeding, or ulcerations.

A favorite location for the papilloma in cattle is the udder and teats, where they may develop in such numbers as to cover the entire surface and make the animal troublesome to milk. The sides of the head, neck, and shoulders also afford satisfactory conditions for their growth, and are frequently seen to be affected by them.

Treatment.--Warts may be removed with the scissors, twisted off with the fingers, or ligatured by means of a rubber band or horsehair. The roots should then be cauterized with tincture of iron, glacial acetic acid, or lunar caustic. Acids should never be used in removing warts about the eyes or in the mouth. Papillomas of the eyelids sometimes change to cancers and should be removed by taking out a wedge-shaped section of the eyelid. Young cattle should be given arsenic internally in the form of Fowler's solution, 1 tablespoonful twice a day for a 6-months-old calf.

POLYPS.