wunder · LibraryPart 42
Read in the Wunder reader — freeMay 17: Weight, 7.4 kilos. Three hours after it was fed the dog received 0.5 gram caffein by mouth. The test of the urine the next day for sugar was negative, but a trace of albumin was present. It will be noticed that the doses were increased gradually and that symptoms were observed only after the fourth dose of 0.1 gram per kilo. Later meat was substituted for the carbohydrate diet and the administration of caffein was stopped for four days. At the end of this period 100 mg caffein per kilo was fed daily for five days, and the dose was then very gradually increased. Diarrhea occurred twice, but no other symptoms, the second attack having lasted a few days. The following is a complete record of the experiment:
May 19: 0.5 gram caffein 11.45 a. m.
May 20: 0.75 gram caffein 12.45 a. m.
May 21: 0.75 gram caffein 12 noon; no sugar, no albumin in urine.
May 22: 0.75 gram caffein; urine, same condition found; no symptoms.
May 23: Weight, 7.5 kilos; no caffein.
May 24: 0.75 gram caffein; tremors very marked.
May 25: No caffein.
May 26: 0.75 gram caffein.
May 27: 0.75 gram caffein.
May 28: 0.75 gram caffein.
May 29: 1 gram caffein in two doses of 0.75 and 0.25 gram.
May 30: No caffein.
May 31: No caffein; meat diet exclusively.
June 1: No caffein; meat diet exclusively.
June 2: No caffein; no sugar, no albumin in urine.
June 3: Weight, 7.6 kilos; 0.75 gram caffein; no sugar in urine.
June 4: Weight, 7.3 kilos; 0.75 gram caffein; no sugar in urine.
June 5: Weight, 7.5 kilos; 0.8 gram caffein; drank 500 cc water; ate 200 grams meat.
June 6: Weight, 7.4 kilos; 0.8 gram caffein; 500 cc urine; drank 500 cc water; ate 200 grams meat; no symptoms.
June 7: Weight, 7.7 kilos; 0.8 gram caffein 10 a. m.; 400 cc urine, 500 cc water, 200 grams meat.
June 8: Weight, 7.5 kilos; 0.9 gram caffein, 450 cc urine, 1 p. m.; 200 grams meat, 500 cc water.
June 9: Weight, 7.6 kilos; 0.9 gram caffein, 1 p. m.; 500 cc water, 200 grams meat and bone dust; diarrhea and restlessness all afternoon.
June 10: Weight, 7.6 kilos; 1 gram caffein, 500 cc water, 200 grams meat, 480 cc urine.
June 11: Weight, 8 kilos; 1 gram caffein, 470 cc urine, 500 cc water, 200 grams meat.
June 12: Weight, 7.8 kilos; 1 gram caffein, 710 cc urine, 500 cc water, 200 grams meat.
June 13: 450 cc urine, 500 cc water, 300 grams meat.
June 14: Weight, 7.9 kilos; 1.2 grams caffein, 500 cc water, 300 grams meat, 490 cc urine.
The Toxicity of Caffein: an Experimental Study on Different Species of Animals · The Wunder Library — complete classics, free to read, with narration.