Part 38

(2) Condition very poor; not fed.

September 1: Found dead. Autopsy: Lungs congested and adhering to the pleura; extensive inflammation of pleura; liver slightly enlarged and congested; mucosa of stomach and small intestines slightly congested; other organs normal.

Rabbit 390. Belgian, male.

Given 1 cc of 1 per cent caffein to each 100 grams through stomach tube.

------------+---------+------------ Date. | Weight. | Treatment. ------------+---------+------------ | Grams.| cc. Aug. 17 | 1,490 | 15.0 Aug. 18 | 1,370 | 14.0 Aug. 19 | 1,365 | 13.5 Aug. 20 | 1,340 | 13.5 Aug. 21 | 1,265 | 12.5 Aug. 22(1) | | Aug. 23 | 1,120 | 11.0 ------------+---------+------------

(1) Not fed.

August 24: Found dead 9 a. m. Autopsy: Heart and lungs appeared normal; abdominal viscera showed no apparent pathologic change other than coccidial infection of the liver and fullness of the blood vessels.

Rabbit 392. Maltese, female.

Given 1 cc of 1 per cent caffein to each 100 grams through stomach tube.

------------+---------+----------- Date. | Weight. | Treatment. ------------+---------+----------- | Grams.| cc. Aug. 17 | 1,265 | 12.5 Aug. 18 | 1,275 | 12.5 Aug. 19 | 1,240 | 12.5 Aug. 20 | 1,220 | 12.0 Aug. 21 | 1,245 | 12.5 Aug. 22(1) | | Aug. 23 | 1,180 | 12.0 Aug. 24 | 1,190 | 12.0 Aug. 25 | 1,155 | 11.5 Aug. 26 | 1,140 | 11.5 Aug. 27 | 1,140 | 11.5 Aug. 28(1) | | Aug. 29 | 1,115 | 11.0 Aug. 30 | 1,080 | 11.0 Aug. 31 | 1,020 | 10.0 Sept. 1 | 995 | 10.0 Sept. 2 | 930 | 9.0 ------------+---------+-----------

(1) Not fed.

Died at 3 p. m. September 2. Autopsy: The stomach and small intestines showed numerous small hemorrhagic spots; a thick coating of mucus surrounded the contents of the stomach; the other organs were apparently normal.

Rabbit 403. Black.

Given 1 cc of 1 per cent caffein for each 100 grams.

------------+---------+----------- Date. | Weight. | Treatment. ------------+---------+----------- | Grams.| cc. Aug. 20 | 1,640 | 16.5 Aug. 21 | 1,640 | 16.5 Aug. 22(1) | | Aug. 23 | 1,490 | 15.0 Aug. 24 | 1,515 | 15.0 Aug. 25 | 1,475 | 15.0 Aug. 26 | 1,390 | 14.0 Aug. 27 | 1,330 | 13.5 Aug. 28(1) | | Aug. 29 | 1,130 | 11.5 Aug. 30 | 1,055 | 10.5 ------------+---------+-----------

(1) Not fed.

August 31: Found dead at 3 p. m. Autopsy: Extensive gastroenteritis; liver enlarged and congested; spleen slightly congested; peritoneum thickened and congested; other organs normal.

Rabbit 884. Black, female.

Given 1 cc of 1 per cent caffein for each 100 grams through stomach tube.

------------+---------+----------- Date. | Weight. | Treatment. ------------+---------+----------- | Grams.| cc. Aug. 16 | 1,195 | 12.0 Aug. 17 | 1,205 | 12.0 Aug. 18 | 1,140 | 11.5 Aug. 19 | 1,180 | 12.0 Aug. 20 | 1,145 | 11.5 Aug. 21 | 1,145 | 11.5 Aug. 22(1) | | Aug. 23 | 1,005 | 10.0 Aug. 24 | 1,035 | 10.5 Aug. 25 | 990 | 10.0 Aug. 26 | 960 | 9.5 Aug. 27 | 955 | 9.5 Aug. 28(1) | | Aug. 29 | 870 | 9.0 Aug. 30(2) | 850 | 8.5 Aug. 31 | 810 | 8.0 Sept. 1 | 740 | 7.5 ------------+---------+-----------

(1) Not fed.

(2) Poor condition, mucus from rectum.

September 2: Found dead at 9 a. m. Autopsy: The mucosa of stomach showed numerous hemorrhagic spots; the first portion of the small intestines was slightly congested; the other organs were apparently normal in appearance.

Rabbit 383. Belgian, female.

Given 1 cc of 1 per cent caffein for each 100 grams through stomach tube.

-----------+---------+------------ Date. | Weight. | Treatment. -----------+---------+------------ | Grams.| cc. Aug. 16 | 995 | 10.0 Aug. 17 | 1,005 | 10.0 Aug. 18 | 990 | 10.0 Aug. 19 | 895 | 9.0 Aug. 20 | 945 | 9.5 Aug. 21 | 965 | 9.5 Aug. 22(1) | | Aug. 23 | 875 | 9.0 Aug. 24 | 855 | 8.5 Aug. 25 | 850 | 8.5 Aug. 26 | 785 | 8.0 Aug. 27 | 710 | 7.0 -----------+---------+------------

(1) Not fed.

August 28: Found dead at 9 a. m. Autopsy: Lungs, heart, and spleen apparently normal; liver infected with coccidia; stomach apparently normal; walls of small intestines injected; colon marked congestion and hemorrhagic; kidneys hemorrhagic.