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Part 16

The Toxicity of Caffein: an Experimental Study on Different Species of Animals · William Salant — chapter 16 of 53 · ~407 words · public domain

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October 14: Alive, no symptoms.

Rabbit 426. Belgian hare, female. Weight, 1,425 grams.

September 27: 7 cc 2 per cent caffein injected into the lumbar muscles at 10.30 a. m.; 2 p. m., reflexes increased.

September 28: Rabbit normal.

October 5: Weight, 1,425 grams; 2.55 p. m., 9 cc 2 per cent caffein injected into lumbar muscles; 3.05 p. m., reflexes increased.

October 13: Weight, 1,405 grams; 10.30 a. m., 10 cc 2 per cent caffein (142 mg per kilo) injected; 11 a. m., no symptoms; 11.30 a. m., reflexes increased.

October 14: Rabbit alive, no symptoms.

Rabbit 427. Belgian hare, female. Weight, 1,780 grams.

September 27: 9 cc 2 per cent caffein injected into the lumbar muscles; 2 p. m., reflexes increased.

September 28: Rabbit normal.

October 5: Weight, 1,850 grams; 3 p. m., 11.5 cc 2 per cent caffein injected into lumbar muscles; 3.10 p. m., reflexes increased.

October 13: Weight, 1,830 grams; 10.40 a. m., 14 cc 2 per cent caffein (153 mg per kilo) injected into lumbar muscles; 11 a. m., no symptoms; 11.30 a. m., reflexes increased.

October 14: Rabbit alive, no symptoms.

Rabbit 453. Belgian hare, male. Weight, 1,160 grams.

October 12: 3.45 p. m., 11.5 cc 2 per cent caffein in aqueous solution injected into lumbar muscles; 4.15 p. m., reflexes increased; 4.30 p. m., paralyzed.

October 13: 9 a. m., found dead. Autopsy: Gastric mucosa hemorrhagic; liver darkened; other organs normal.

Rabbit 455. Belgian hare, gray, female. Weight, 1,185 grams.

October 12: 3.30 p. m., 11.5 cc 2 per cent caffein injected into the lumbar muscles; 4 p. m., reflexes increased.

October 13: Rabbit weighed 1,070 grams, no symptom of caffein poisoning, reflexes normal; 10.30 a. m., 10 cc 2 per cent caffein injected into the lumbar muscles; 11.30 a. m., jumped off the table, had attack of convulsions and died. Autopsy: Findings same as in No. 453.

Rabbit 428. Belgian hare, gray, male. Weight, 1,650 grams.

October 5: 4 p. m., 14.8 cc 2 per cent caffein (0.18 gram per kilo) injected into the lumbar muscles.

October 6: Found dead.

Rabbit 429. Belgian hare, male. Weight, 1,340 grams.

October 5: 4 p. m., 13.5 cc 2 per cent caffein (0.2 gram per kilo) injected into lumbar muscles.

October 8: Rabbit found dead.

SERIES D.

Further experiments making injections into both the lumbar and the gluteal muscles, were made in this series.

Rabbit 577. Gray male. Weight, 1,380 grams.

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