Part 36

Nom. Vulg.--Anis, Sp.; Fennel, Eng.

Coriandrum sativum, L. (Cuminum cynimum, Wall.)

Nom. Vulg.--Cominos, Calantro, Sp.; Coriander, Eng.

Uses.--The fruit of both species has the same therapeutical application being stomachic and carminative par excellence. It yields an aromatic essential oil with stimulant properties, popular because of its agreeable odor and taste.

As a rule the infusion is given in doses of one liter a day (15-30 grams of the seeds to one liter of water). The essence and the alcoholate are also employed, the former obtained by distillation, the latter by macerating the fresh seeds in alcohol. The dose of the essence, 4-8 drops on a piece of sugar or in potion; the alcoholate, 2-10 grams in sweetened water or infusion of aromatic herbs.

Both plants are official in the Spanish Pharmacopoeia and they and their preparations are common in all drug stores.

Habitat.--Common, cultivated in the gardens and well known.

Botanical Description.--F. vulgare: Aromatic, stout, smooth herb, 4-6° high. Leaves with many slender thread-like divisions. Large umbel of yellow flowers, no involucre and no involucels. C. sativum: Low aromatic herb, leaves pinnately compound, small umbels with few rays, flowers white.

CORNACEÆ.

Dogwood Family.

Alangium Lamarkii, Thwaites. (A. decapetalum, hexapetalum and tomentosum, Lam.)

Nom. Vulg.--(?)

Uses.--According to Mooden Sheriff, the root bark is an efficient emetic in doses of 3 grams. In smaller doses it is febrifuge and produces nausea. The bark is extremely bitter; its reputation in the treatment of skin diseases is undeserved. It is a good substitute for ipecac, having given good results in all conditions in which the latter is indicated, with the exception of dysentery.

The febrifuge dose is 0.35-0.60 gram; alterative, 0.15-0.30 gram.

It is furthermore prescribed in India for syphilis and leprosy and is one of the many remedies used for the bites of rabid animals. The bruised leaves are applied to the joints of rheumatic patients.

Botanical Description.--A tree 20-30 meters high, leaves alternate, persistent, petiolate, no stipules, oblong, dentate, acuminate, pinnately nerved. Flowers whitish, regular, hermaphrodite, in terminal cymes. Receptacle concave. Calyx short, 10-toothed. Corolla, 10 narrow, elongated ribbon-like petals. Stamens 30-40, filaments free and glabrous. Ovary inferior, held in the concavity of the receptacle, one-celled, with 1 seed, crowned by an epigynous disc, above which rises a simple style with dilated stigma. Fruit a globose drupe, crowned by the calyx, with 10 inconspicuous ribs. The putamen encloses an albuminous kernel.

Habitat.--The mountains of San Mateo.

DICOTYLEDONOUS, GAMOPETALOUS.

RUBIACEÆ.

Madder Family.

Hymenodictyon excelsum, Wall. (H. Horsfieldii, Miq.; Chinchona excelsa, Roxb.; Exostema Philippicum, Blanco.)

Nom. Vulg.--Huligaga, Tag.

Uses.--The bark of this tree has a wide reputation in India as a tonic and febrifuge. The inner layer of the bark possesses astringent and bitter properties much like quinine. Ainslie states that it is used in India to tan hides and therapeutically where an astringent is required. O'Shaughnessy experimented with it in the hospital of the Medical College of Calcutta and reported good tonic and antipyretic effects.

In 1870, according to Dymock, Broughton analyzed the fresh bark and reported that the bitter taste was due to esculin, which after drying and coming in contact with decomposing organic matter is transformed into the almost tasteless esculetin. Naylor studied the bark at a later period, and attributed the bitterness to an alkaloid that he named hymenodictyonine. This substance exists in the form of a gelatinous mass, cream-colored, very hygroscopic. An ethereal solution, carefully evaporated, deposits it in the form of crystals. Its empirical form is C23H40N2; it is probably volatile and is notable for its lack of oxygen. It differs from quinoidine in that it is inactive (?) and that in combination with platinum it retains less of this metal than does quinoidine. It differs from paricine in its proportion of hydrogen, and from berberine in containing more carbon. In the presence of sulphuric acid its solution assumes a yellow color, changing to wine-red and then to dark red. Naylor extracted another principle which he found combined with the alkaloid in a soda precipitate of the latter; it is a product of the decomposition of a glucose, the formula of which is C25H49O7. This compound remains insoluble when the alkaloid is treated with ether. Repeated boiling in alcohol renders it colorless. It is bitter, soluble in alcohol and dilute acids; insoluble in ether and chloroform. Reaction, neutral.

Botanical Description.--A large tree, with leaves opposite, oval, entire, acute, downy. Petioles long, flat above, with 2 stipules. Flowers axillary, in compound verticillate racemes. Calyx adherent, with 5 promptly deciduous teeth which leave a scar that also disappears. Corolla much longer than the calyx, funnel-form, the limb 5-cleft. Stamens 5, inserted near the middle of the tube. Filaments rudimentary. Anthers 2-celled. Style longer than the corolla. Stigma globose. Seed-vessel rather rough, ovoid, flattened, of 2 compartments, where are inserted numerous seeds, imbricated, circular, encircled by an entire wing.

Habitat.--Angat and the woods of San Mateo. Blooms in August. (P. Blanco states further that this tree grows to a height of about 3 yards in Angat and that it exhales a strong odor resembling that of vinegar at times, and again like that of tobacco.)

Oldenlandia corymbosa, L. (O. biflora, Lam.; O. ramosa, Roxb.; O. herbacea and serabrida, DC.; O. burmaniana, Mig.)

Nom. Vulg.--Doubtful.