Part 30

Dose.--60-200 grams a day.

The juice of the leaves is also used to treat diarrhoea. A Hindoo physician, Bhavaprakasa, advises the following receipt:

Juice of leaves of lomboy } Juice of leaves of manga } aa 4 grams. Pulp of Terminalia chebula }

Give in one dose in a little goat's milk and honey.

A sort of wine of very agreeable taste is made from the fruit juice. Lately the powdered seed has been recommended in the treatment of glycosuria or at least it has been stated that its internal use lessens and finally abolishes the glucose from the urine of the patient. It has even been affirmed that while under this treatment the patient may eat glucose-forming foods without fear of glycosuria supervening.

The chemical composition of the seeds are as follows:

Essential oil Traces. Chlorophyl and fatty matters 0.37 Resin soluble in alcohol and ether 0.30 Gallic acid 1.65 Albumin 1.25 Pigment soluble in water 2.70 Water 10.00 Insoluble residuum 83.73 ------ 100.00

Dujardin-Beaumetz has tested the therapeutic value of these seeds in diabetes but with negative results. Scott has maintained that by adding the powdered seed to a mixture of malt and starch, fermentation is impeded; but Dr. Villy in the laboratory of Dujardin-Beaumetz has demonstrated that such is not the case. Contrary to the opinions of those physicians who stated that "jambul" was capable of causing the glucose to disappear from the urine of diabetic patients without concurrent diabetic regimen, Dujardin-Beaumetz observed in his trials of the drug that the slightest relaxation of the regimen was followed by an increase of glucose. Under the influence of the medicine in doses of 2-10 grams daily, at the same time maintaining a strict diabetic diet, the Parisian therapeutist noted that the glucose disappears from the third to the fifth day; but this occurred only in cases of medium intensity, whereas in severe cases the medication produced no effect. Upon stopping the treatment the sugar reappeared.

Botanical Description.--A tree, 15-20° high, with leaves opposite, acute, entire, ovate, lustrous, very smooth. Flowers in racemose panicles with peduncles opposite. Calyx superior, with 5 small teeth and a deciduous cover composed of many orbicular pieces joined below. Corolla none. Stamens numerous, inserted on the edge of the calyx. Stigma pointed. Fruit black, oval, crowned with the calyx; one long cylindrical seed with membranaceous epidermis.

Habitat.--Common all over the Archipelago. Blooms in February.

MELASTOMACEÆ.

Melastoma malabatrichum, L. (M. obvolutum, Jack.; M. aspera and obvoluta, Blanco.)

Nom. Vulg.--Granatis, Tag.

Uses.--A decoction of the leaves is of use as an astringent in diarrhoea and dysentery. A decoction of the bark is used as a gargle for aphthæ and catarrhal sore throat, and as a wash for ulcers and the itch.

The fruit is edible, resembling slightly the currant; it has doubtless received the name "granatis" on account of its many seeds.

Botanical Description.--Small tree, with opposite branches, their ends covered with hairs. Leaves opposite, 3-nerved, 1' long, very rough with short hairs. Flowers carmine, in terminal panicles. Stamens 10. Filaments alternating violet and straw-color.

Habitat.--Mountains of Angat and San Mateo.

LYTHRACEÆ.

Loosestrife Family.

Ammannia vesicatoria, Roxb. (A. baccifera, L.; A. Indica, Lam.; A. debilis and Celosia mana, Blanco.)

Nom. Vulg.--Bias pogo, Tag.; Blistering Ammannia, Indo-Eng.

Uses.--The leaves contain an irritant and acrid principle that renders them vesicant when applied to the skin. The Pharmacopoeia of India quotes Sir W. O'Shaughnessy to the effect that plasters made of the bruised leaves even when renewed every half hour require 24 hours to raise a blister and at the same time cause severe pain. He found it much more painful than cantharides and much less prompt to act. Dr. Dymock has prepared an ethereal tincture of the leaves and obtained with it results very different from those just mentioned; this is not surprising in view of the fact that the tincture holds in solution in a small quantity of ether, a considerable amount of the vesicant principle. This tincture has the same color as the "epispastic" of the English Pharmacopoeia, causes less pain and rapidly raises a good blister, facts of which I have convinced myself by the use of a small quantity sent me from Bombay in 1891.

Dr. Bholanauth Bose recommends the internal use of the juice of the leaves as a remedy for chronic diseases of the spleen; this treatment, however, has caused severe pain and is absolutely uncertain in effect.

In Concan the juice of the leaves is given mixed with food to animals in heat, for its anaphrodisiac action. The fresh or dried plant is given in decoction mixed with ginger in intermittent fevers.

If the ethereal tincture be evaporated a resinous residue remains that has not been studied, but appears to be the vesicant principle. This tincture should be made from the dried leaves to avoid hydration of the ether.

Botanical Description.--A small plant with stem red, straight, quadrate, ramose. Leaves opposite, lanceolate, and fringed with hairs. Flowers axillary, small, red, solitary. Peduncles short. Calyx inferior, bell-shaped, with 8-toothed border, the 4 alternate teeth larger. Corolla none. Nectary bell-shaped, surrounding the ovary, shorter than the calyx, with 4 toothlets which lengthening form the filaments of as many stamens. Anthers 4-celled. Ovary of 4 pluriovulate locules. Style almost wanting. Stigma fluted. Seed vessel glabrous, horizontally dehiscent, containing 15 or more angular seeds joined to a common axis.

Habitat.--It grows in the marshes of Mandaloyon.

Lawsonia alba, Lam. (L. spinosa, L.; L. inermis, Roxb.)