Part 15

3. Total number of persons inoculated One inoculation 2,983 Two inoculations 3,675 Three inoculations 4,626 Four inoculations 10,053 —————— Total 21,337

4. Cases influenza developed after No inoculations 2,133 23% One inoculation 745 25% Two inoculations 776 21% Three inoculations 794 17% Four inoculations 1,280 12% —————— Total 5,728

5. Cases influenza pneumonia developed after No inoculations 804 37% One inoculation 356 48% Two inoculations 403 52% Three inoculations 321 40% Four inoculations 459 36% —————— Total 2,343

6. Deaths from influenza and “flu Pneumonia” after No inoculations 104 4.7% One inoculation 32 4.3% Two inoculations 33 4.2% Three inoculations 21 2.6% Four inoculations 33 2.5% —————— Total 223 3.9%

CHART II.

H. C. FRICK COKE COMPANY.

STATISTICAL REPORT ON INOCULATION AGAINST INFLUENZA.

1. Number of employees who had influenza 5,248 31.4%

2. Number of employees who did not have influenza 11,464 —————— Total number of employees 16,712

3. Total number of persons inoculated No inoculations 3,122 One inoculation 2,483 Two inoculations 2,548 Three inoculations 3,550 Four inoculations 5,009 —————— Total 13,590

4. Cases influenza developed 47.9% after No inoculations 1,495 of (3 One inoculation 634 25.5% Two inoculations 770 30.2% Three inoculations 1,078 30.4% Four inoculations 1,271 25.0% —————— Total 5,248

5. Cases influenza pneumonia 6.3% developed after No inoculations 94 of (4 One inoculation 33 5.2% Two inoculations 42 5.4% Three inoculations 69 6.4% Four inoculations 85 6.7% —————— 6.1% Total 323 of (4 total

6. Deaths from influenza and “flu 2.0% No inoculations 30 of (4 One inoculation 13 2.0% Two inoculations 21 2.9% Three inoculations 16 1.5% Four inoculations 37 2.9% —————— 2.2% Total 117 of (4

CHART III.

BESSEMER & LAKE ERIE RAILROAD.

STATISTICAL REPORT ON INOCULATION AGAINST INFLUENZA.

1. Number of employees who had influenza 1,275 24%

2. Number of employees who did not have influenza 3,986 —————— Total number of employees 5,261

3. Total number of persons inoculated No inoculations 3,091 One inoculation 232 Two inoculations 249 Three inoculations 479 Four inoculations 1,210 —————— Total 2,170

4. Cases influenza developed after No inoculations 705 55% One inoculation 111 48% Two inoculations 91 36% Three inoculations 129 27% Four inoculations 239 19% —————— Total 1,275

5. Cases influenza pneumonia 40% developed after No inoculations 283 of (4 One inoculation 75 67% Two inoculations 59 64% Three inoculations 51 42% Four inoculations 69 28% —————— Total 537

6. Deaths from influenza and “flu 5.6% Pneumonia” after No inoculations 40 of (4 One inoculation 5 4.5% Two inoculations 0 Three inoculations 0 Four inoculations 3 4.3% —————— Total 48

Charts I and III show a decrease in the incidence of influenza in direct proportion to the number of inoculations given. This finding would have been very important had vaccination been completed before the epidemic appeared. There is, however, no convincing evidence in either of these charts that the vaccine cut down the relative number of pneumonias, or decreased the death rate to any appreciable extent. Chart I also shows the interesting fact that influenza occurred slightly more often among those who had one inoculation than among those who were not vaccinated at all.

Chart II would indicate that influenza occurred much less frequently in the vaccinated than in the control group, but a closer analysis brings out the contradictory finding that influenza occurred at the same rate in the group of 634 persons who had only 1 dose that it did in the group of 1,271 who completed the course.

The reports from the separate communities were so conflicting that to attempt to analyze them leads only to confusion.

No reports of harmful effects from the use of the vaccine were received, and several physicians who attended sick employees say that, even though the figures do not show it, they feel certain that the vaccinated persons in general were not as sick as those who were not vaccinated.

On account of the conditions under which the vaccinations were done and the reports compiled, Dr. Sherman has not felt justified in making a report, fearing that erroneous conclusions might be drawn from the data. We are greatly indebted to him for the use of his reports, without which our account of the influenza epidemic in Pittsburgh would have been very incomplete.

2. Another large steel corporation who used vaccine but asked that their names be withheld furnished the following report. During the epidemic the company offered free vaccination to its 27,000 employees and their families. Commercial mixed vaccines were used, three injections given, and vaccination begun on October 19, which was about the time of the peak of the epidemic in Pittsburgh. The results include a record of all employees who lost over six days between October 1 and November 30.