Part 1

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SOME CONSTITUENTS OF THE POISON IVY PLANT (RHUS TOXICODENDRON)

DISSERTATION

SUBMITTED TO THE BOARD OF UNIVERSITY STUDIES OF THE JOHNS HOPKINS UNIVERSITY IN CONFORMITY WITH THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY

BY WILLIAM ANDERSON SYME

1906

1906 THE SUN JOB PRINTING OFFICE BALTIMORE

Transcriber's Note: Underscores around words indicates italics while an underscore and curly brackets in an equation indicates a subscript.

CONTENTS.

Acknowledgments 4

Literature 5

Introduction 7

Work of Khittel 11

Work of Maisch 12

Work of Pfaff 13

Experimental 14

Gallic Acid 18

Fisetin 20

Rhamnose 23

The Poison 28

Potassium Permanganate as a Remedy for Rhus Poisoning 35

Summary 37

Biography 38

ACKNOWLEDGMENTS.

The author desires to avail himself of this opportunity to tender his thanks to those under whose guidance he has worked while a student at the Johns Hopkins University, namely to Professors Remsen, Morse, Jones, and Andrews, and to Doctors Acree and Tingle for instruction in lecture room and laboratory.

He is especially indebted to Dr. S. F. Acree, at whose suggestion this research work was undertaken, for counsel and assistance in its prosecution.

He would also thank Messrs. Parke, Davis and Co., of Detroit, Mich., for the preparation of the crude material used in this investigation, and the U. S. Department of Agriculture, Washington, D. C., for electrotypes of figures 17, 18, and 19 in Bulletin No. 20, Division of Botany.

LITERATURE.