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CHAPTER IX

Immunity in Infective Diseases · Elie Metchnikoff — chapter 9 of 39 · ~126 words · public domain

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THE MECHANISM OF ACQUIRED IMMUNITY AGAINST MICRO-ORGANISMS 250 Cytases and fixatives.—Only the latter are augmented in the immunised organism.—Properties of the fixatives.—Difference between them and the agglutinative substances.—The part played by the latter in acquired immunity.—Protective property of the fluids of the immunised organism.—Stimulant action of the body fluids.—The protective power of serum cannot serve as a measure of acquired immunity.—Examples of acquired immunity in which the serums exhibit no protective power.—Phagocytosis in acquired immunity.—Negative chemiotaxis of leucocytes.—Theory of attenuation of micro-organisms by the fluids of immunised animals.—Refutation of this theory.—Phagocytosis acts without requiring any previous neutralisation of the toxins.—The origin of the fixative and protective properties of the body fluids.—The relation between these properties and phagocytosis.—The side-chain theory of Ehrlich and the theory of phagocytes.

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