Part 52

Dr. Paris, in his admirable work on Materia Medica, has justly observed, "that observation or experiment upon the effects of medicine is liable to a thousand fallacies, unless it be carefully repeated under the various circumstances of health and disease, in different climates, and on different constitutions." This has been the main object of the homoeopathist; and a further quotation from the above distinguished writer will illustrate the importance of their labours. "It is impossible to cast our eyes over such multiplied groups (of medicinal substances) without being forcibly struck with the palpable absurdity of some, the disgusting and loathsome nature of others, the total want of activity in many, and the uncertain and precarious reputation of all, without feeling an eager curiosity to inquire, from the combination of what causes it can have happened that substances at one period in the highest esteem, and of generally acknowledged utility, have fallen into total neglect and disrepute. That such fluctuation in opinion and versatility in practice should have produced, even in the most candid and learned observer, an unfavourable impression with regard to the general efficacy of medicines can hardly excite our astonishment, much less our indignation; nor can we be surprised to find that another portion of mankind has at once arraigned physic as a fallacious art, or derided it as a composition of error and fraud. A late foreign writer, impressed with this sentiment, has given the following flattering definition of our profession: Physic is the art of amusing the patient, while Nature cures his disease."

With such a lamentable view of the practice of medicine, can we be too thankful to those observers who strenuously endeavour to rescue it from the dark trammels in which prejudice and interested motives have bound it? In no country more than in Great Britain is such an investigation desirable. We have become proverbial from our incessant abuse of a farrago of medicinal substances; and what is usually termed an elegant prescription signifies an amalgam of various drugs and preparations, which most probably, by their affinities, neutralize the expected effects of each other; for, however great and flattering may have been the discoveries of modern chemistry, many of these affinities are unknown to us. Surely when our labours cannot detect any difference in the component parts of the purest Alpine atmosphere and the deleterious air of a loathsome dungeon, we cannot expect to form a correct idea of pharmaceutic combinations.

The mere hopes of being able to relieve society from the curse of constant drugging, should lead us to hail with gratitude the homoeopathist's investigations. That many physicians, but especially apothecaries, who live by overwhelming their patients with useless and too frequently pernicious medicines, will warmly, nay furiously inveigh against any innovation of the kind, must be expected as the natural result of interested apprehension; and any man who aims at simplicity in practice will be denounced as guilty of medical heresy. Have we not seen inoculation and vaccination branded with the most opprobrious epithets, merely because their introduction tended to diminish professional lucre?

In these remarks upon medicinal combinations, it is not meant to infer, that, because they are chemically incompatible, they are ineffectual,--experience has proved the contrary; but no one will contend that, if we can attain the same beneficial results from a single ingredient, administered in small quantities and at distant periods, as from the exhibition of repeated and nauseous doses of pills, powders, draughts, potions, &c. which hang over the bed of sickness, nay, of slight derangements, like the sword of Damocles, we have not effected a most salutary reform in the practice of physic. It is related of one of these ingenious and industrious practitioners, that, having seen a prescription, that only contained half a dozen medicines, he exclaimed, "What! nothing more?" To which the prescriber replied, "If you choose, sir, we'll step over to the apothecary, and see what else he has in his shop."

Specifics may be divided into two classes; the one producing a peculiar effect upon particular organs, the other producing general results. Thus, the action of cantharides and digitalis on the urinary system, of emetics on the stomach, of certain purgatives on the small intestines, and of others on the large ones, are generally known; whereas the action of mercury and opium is still a matter of controversy. A study of these effects constitutes the chief object of the homoeopathist; and, having determined their peculiar action, these medicinal agents are given singly, and, as we have already observed, in the most minute doses.

It is this division into infinite fractions that has drawn upon the homoeopathic practice the denunciation of the allopathic physicians, as it is considered utterly impossible that such imponderable particles can produce any beneficial or prejudicial effect; and the Academy of Medicine of Paris, when officially condemning the doctrine, asserts, in support of this argument, that great danger arises from it "in frequent and serious cases of disease, where the physician may do as much injury, and cause no less mischief, by ineffectual means as by those which are prejudicial."

This is perhaps one of the most important points of the homoeopathic doctrine. If these fractional doses are inert, and yet the disease is cured, then must the successful treatment be solely ascribed to the dietetic regimen and the efforts of nature. However, experience has afforded abundant proofs that these infinite atoms do produce positive and evident effects. What appears to our feeble organs an atomic fraction may produce phenomena on the organism which we cannot comprehend, but should not therefore be denied. Let one grain of iodine be dissolved in one thousand five hundred and sixty grains of water, the solution will be limpid; let two grains of starch be dissolved in two ounces of water and added to the first solution, and the liquor will forthwith assume a blue tint. In this experiment the grain of iodine has been divided into 1/15360. Dissolve the four-hundredth part of one grain of arsenic in four hundred thousand parts of water, and the hydric-sulphite will bring it into evidence. Let a five-thousandth part of arseniate of ammonia be dissolved in five hundred thousand parts of water, and the addition of the smallest proportion of nitrate of silver will obtain a yellow precipitate. Numerous experiments of a similar nature may be daily resorted to, to prove that the most minute particles of two substances possessed of chemical affinities may be brought into action, although diluted ad infinitum. But the power that the smallest particle possesses in producing natural phenomena cannot be more evidently proved than by Spallanzani's experiments in fecundation. This physiologist having wrapped up a male frog in oil-silk, fecundation could not take place; but having collected on the point of a camel-hair pencil a particle of the fecundising fluid, he succeeded in vivifying thousands of eggs. Surprised at this result, he dissolved three grains of the secretion in a pound of water, and one globule of the solution was endowed with the same faculty. In this case the globule of water only contained 1/2994687500 part of one grain. This curious experiment has been tried with a similar result by Prevost and Dumas. How imponderable and impalpable must be the effluvium which enables the dog to track his master for miles! the particle of atter of roses that perfumes a whole chest of clothes! and what must the power of the aroma be which is preserved for thousands of years in some Egyptian mummies! Would the vulgar believe in the wonders of the solar and gaseous microscopes unless they were exposed to view? In these we behold in amazement myriads of individuals in one drop of fluid, each of them as perfect in organization as the mighty mammoth of old or the sagacious elephant of our days, endowed with distinct habits, destructive and reproductive propensities and faculties.

It has been advanced by the opponents of homoeopathy that the insignificant dose of three or four medicinal globules cannot possess any power, since one might swallow a thousand of them with impunity. To this it is answered, that it is only under certain morbid conditions that these medicines act by their homoeopathic affinities. Moreover, it is well known that small doses of medicinal substances will frequently produce more powerful effects than larger quantities. Tartar-emetic, sugar of lead, calomel, afford daily instances of this fact; and it is also admitted that many substances act differently upon the healthy or the sick. An individual in health can take any food without apprehension; but when his functions are deranged, the slightest imprudence in regimen may lead to serious consequences. There are primordial and inscrutable peculiarities in our constitution that cannot be accounted for; and the medicine which relieves one patient will aggravate the sufferings of others. The exhalations of the American rhus are deadly to some persons, but innocuous to others; and many poisons which cause instantaneous death to some animals may be given with safety to others. Whence has arisen the controversy regarding damp sheets, which many maintain are not dangerous, simply from the fact that a healthy person with a vigorous circulation may sleep in them with impunity, when a feeble and languid subject will be exposed to some dangerous determination of blood?

A learned writer already quoted thus expresses himself on this matter: "The virtues of medicines cannot be fairly nor beneficially ascertained by trying their effects on sound subjects, because the peculiar morbid condition which they are calculated to remove does not exist." It may be said that this observation militates against the homoeopathic experiments, and to a certain extent it evidently does; but it cannot be inferred that because a medicinal substance will occasionally act differently in health and in disease, that it may not frequently operate in a similar manner when the morbid condition does prevail, since it is generally admitted that medicines act in a relative manner according to the state of the system. Hence classifications of medicines are too frequently erroneous and imperfect. The doses of medicines determine their effects. Linnaeus says, "Medicines differ from poisons, not in their nature, but in their dose;" and Pliny tells its aphoristically, "Ubi virus, ibi virtus." According to their doses, medicines will produce a general or a local effect; and Dr. Paris, whom I feel much gratification in quoting, lays down as a rule that "substances perfectly inert and useless in one dose may prove in another active and valuable." It would be foreign to my purpose to enter more fully into this most important subject; but the cases which shall be adduced will be deemed sufficient to convince the most incredulous, of the power of homoeopathic doses.

Those who have denied this property have boldly attributed homoeopathic cures to dietetic means. Admitting this statement by way of argument, surely, if any observer, by ascertaining the peculiar action of our ingesta, can so regulate the regimen as to produce salutary effects without the aid of medicine, mankind would be most essentially benefited. How many persons do we not daily meet with, who have never taken any medicine since their childhood, when maternal care strove to destroy their digestive organs with apothecary's stuff, and who regulate their functions by mere attention to their mode of living. I know one gentleman, a physician, who relieves constipation by green chilies; another, with cold milk; a third, with warm milk: in some habits spinach and sorrel will act as a powerful and safe aperient; in others, cheese, or a hard egg, will operate in a contrary way. Fermented and spirituous liquors all possess specific properties. Some gouty persons cannot drink Claret without bringing on a paroxysm, and others dread a glass of Champagne or Burgundy. Nay, different wines have been known to bring on arthritic attacks in particular parts; and I have known Champagne to produce gout in the wrist, and Burgundy in the knee, in subjects who under other circumstances never experienced the disorder in those articulations. Our peculiar aversion, nay, our dread, of various alimentary substances are well known. The odour of cheese, of strawberries, have occasioned fainting and convulsions; and in certain constitutions, several articles of diet bring on indigestion. In short, the study of our ingesta is one of the greatest importance; and here again the homoeopathist is entitled to our best thanks.

This investigation will moreover prompt physicians to be more attentive in inquiring into the various effects of alimentary and medicinal substances on their patients. Instead of hastily drawing out routine prescriptions for such and such a disorder, they will accurately ascertain the physical and moral condition of the subject, taking into due consideration previous habits, predispositions, and pursuits in life. Indeed, it would be desirable that practitioners followed the example of army medical men, who keep an exact register of every individual they attend, and in which is diligently recorded every circumstance connected with the disease and its treatment.

Moral influence has also been called into aid in opposition to this practice, and cures have been attributed to the mere power of fancy and credulity. We have certainly known superstition and mental imbecility to be productive both of good and evil,--to have created some maladies, and cured others; but homoeopathy has succeeded when the patient was unaware of the treatment to which he was submitted. But, conceding the point, and admitting that inert substances, such as starch, (and this experiment was resorted to in Paris,) may have obtained singular beneficial results,--the results of a weak imagination, this circumstance alone would be illustrative of the power of moral agency; and who would not gladly wish for a mental relief in lieu of a nauseating and injurious course of medicine?

Others will exclaim, although the homoeopathist disavows the vis medicatrix naturae, that he solely succeeds by leaving the malady to the salutary efforts of the constitution. Here again we must admit, that, were we to leave many diseases to run their course, we might be more successful in obtaining a cure than by a rash and detrimental interference, founded on the principle that a physician "must order something."

But the facts I am about to record,--facts which induced me, from having been one of the warmest opponents of this system, to investigate carefully and dispassionately its practical points,--will effectually contradict all these assertions regarding the inefficacy of the homoeopathic doses, the influence of diet, or the agency of the mind; for in the following cases in no one instance could such influences be brought into action. They were (with scarcely any exception) experiments made without the patient's knowledge, and where no time was allowed for any particular regimen. They may, moreover, be conscientiously relied upon, since they were made with a view to prove the fallacy of the homoeopathic practice. Their result, as may be perceived by the foregoing observations, by no means rendered me a convert to the absurdities of the doctrine, but fully convinced me by the most incontestable facts that the introduction of fractional doses will soon banish the farrago of nostrums that are now exhibited to the manifest prejudice both of the health and the purse of the sufferer.

CASE I.

A servant-maid received a blow of a stone upon the head. Severe headache, with dizziness and dimness of sight, followed. Various means were resorted to; but general blood-letting could alone relieve the distressing symptoms, local bleeding not having been found of any avail. The relief, however, was not of long duration, and the distressing accidents recurred periodically, when abstraction of blood became indispensable. Reduced by these frequent evacuations, I was resolved to try the boasted "bleeding globules" of the homoeopathist, when, to my great surprise, I obtained the same mitigation of symptoms which the loss of from twelve to sixteen ounces of blood had previously accomplished. Since the first experiment no venesection became necessary, and the returns of the violent headache were invariably relieved by the same means.

CASE II.

An elderly woman was subject to excruciating headache, with an evident determination of blood to the brain. Numerous leeches were constantly applied. The usual remedies indicated in similar affections were resorted to, but only afforded temporary relief. A homoeopathic dose of aconite was given, and the relief that followed was beyond all possible expectation.

CASE III.

My much-esteemed friend Dr. Grateloup of Bordeaux was subject to frequent sore-throats, which were only relieved by local blood-letting, cataplasms, &c., but generally lasted several days, during which deglutition became most difficult. I persuaded him to try a dose of the belladonna, neither of us having the slightest confidence in its expected effects. He took the globules at twelve o'clock, and at five P.M. the tumefaction of the tonsils, with their redness and sensibility, had subsided to such an extent that he was able to partake of some food at dinner. The following morning all the symptoms, excepting a slight swelling, had subsided.

Since this period Dr. G. has repeatedly tried the same preparation in similar cases, and with equal success. In my own practice, I can record seven cases of cynanche tonsillaris which were thus relieved in the course of a few hours.

CASE IV.

H--, a young woman on the establishment of the Countess of --, was suffering under hemiplegia, and it was resolved by Dr. Brulatour and myself to try the effects of nux vomica. At this period the wonders of the homoeopathic practice had been extolled to the skies by its advocates, and we were resolved to give one of their supposed powerful preparations a fair trial. The girl was told that the powder she was about to take was simply a dose of calomel; and on calling upon her the following morning we did not expect that the slightest effect could have been obtained by this atomic dose, when, to our utter surprise, the patient told us that she had passed a miserable night, and described to us most minutely all the symptoms that usually follow the exhibition of a large dose of strychnine. It is but fair to mention that the homoeopathic treatment did not cure the disease; but the manifest operation of this fractional dose, that could not possibly be denied, is a fact of considerable importance.

CASE V.

Mrs. ---- of Brompton, Bow, had laboured under hectic fever for several months, and was so reduced by night perspirations, that she was on the very brink of the grave. Called into consultation, I frankly told her husband that every possible means known in the profession had been most judiciously employed, and that I saw no prospect of obtaining relief. At the same time I mentioned to him that the homoeopathic practitioners pretended that they had found the means of relieving these distressing symptoms, which he might submit to an experimental trial if he thought proper. He immediately expressed his wish that it should be adopted. I gave her a homoeopathic dose of phosphoric acid and stannum; and, to the surprise of all around her, the night sweats did not break out at their usual hour,--three o'clock in the morning. What renders this case still more interesting is the fact of these perspirations recurring so soon as the action of the medicine ceased; a circumstance so evidently ascertained, that the patient knew the very day when another dose became necessary.

CASE VI.

A daughter of the same lady was subject to deafness, which I attributed to a fulness of blood. This cause I clearly ascertained by the relief afforded by the application of a few leeches behind the ear. I was therefore induced, on a recurrence of the complaint, to endeavour to diminish vascular action by a dose of aconite. The effects were evident in the course of four hours, when the deafness and the other symptoms of local congestion had entirely disappeared.

* * * * *