Part 6

GASCOYNE’S OR GASCOIGN’S POWDER.

In the paper by Mr. Slare read before the Royal Society already referred to the author comments with similar severity on the then popular Gascoign’s Powder. As evidence of the fame it possessed he says he had been told that a certain “grandee of the faculty” had got above £50,000 by prescribing this compound. I suppose this meant he had received that amount in fees for prescriptions ordering that medicine. Taking advantage of the reverence in which bezoar was held by that generation, Gascoign’s Powder had assumed as a second title the name of bezoardic powder. It was also known as the Powder of the Black Tops of Crab-claws, from the ingredient in largest quantity. The professed composition of Gascoign’s Powder as given by Mr. Slare was oriental bezoar, white amber, hartshorn in powder, pearls, crabs’ eyes, coral, and black tops of crabs’ claws. Naturally a powder of such costly ingredients was sold at a very high price. Mr. Slare recommends chalk and salt of wormwood as being in all respects as good. The former was cheap enough then; and of the salt he says two pounds could be got for the price of half an ounce of the compound.

VIPERS.

Both in ancient and comparatively modern times vipers have been held in the highest esteem for their medicinal virtues, and viper fat, viper broth, and viper wine are used to this day in some remote parts of Britain, and to a still greater extent on the Continent. In some districts of France heads of vipers enclosed in little silk bags are worn by children to preserve them from croup and convulsions.

It was the addition of vipers to the confection of Mithridates that constituted the principal improvement effected by Andromachus in his composition of the electuary which came to be known as theriakon, and subsequently as theriaca. Therion was Greek for a wild beast, but came to mean specially a venomous serpent, and the compound may have been called theriaca either to indicate that vipers were an important ingredient, or that it would cure their bites.

According to Dr. Mead, Antonius Musa, physician to Octavius Cæsar, was one of the first physicians who recommended the flesh of vipers for medicinal use. Pliny states that he quickly cured inveterate ulcers by this remedy. It is possible, however, that Musa acquired his knowledge of this remedy from a Greek physician named Craterus, who had advised that in certain wasting diseases vipers should be eaten, dressed as fish. In Galen’s time vipers had become common medicines, and were probably taken to some extent as a nourishing food.

Moses Charas studied vipers very closely, and wrote a treatise on their use in medicine (1669) which had a great reputation. He adopted the curious view of Van Helmont that the poison of the viper, which was supposed to be contained in the animal’s saliva, was not there normally, but was created as the effect of rage and terror. According to Charas, the head of the viper, grilled and eaten, would cure its bite, or hung to the neck would cure quinsy. The brain similarly hung on the neck of an infant would greatly assist in cutting the teeth. The skin fastened round the right thigh of a woman was an excellent aid to delivery in childbirth; if given to dogs, cooked or raw, it would cure mange. The fat was a valuable application in gout, or for tumours. Those treatments he had verified by his own experience. Other virtues attributed to vipers were mentioned, but he had not proved them, and could not conscientiously guarantee their existence. One was that the person who swallowed the liver of a viper could not be bitten by any kind of serpent during the ensuing six months.

Madame de Sévigné, was a firm believer in the medicinal value of vipers. Writing to her daughter in 1679 she says: “Madame de Lafayette is taking viper broth, which much strengthens her eyesight.” In 1685 she informs her son: “It is to vipers I am indebted for the abundant health I now enjoy. They temper, purify, and refresh the blood. But it is essential to have the vipers themselves, and not the powder, which is heating unless taken in broth, boiled cream, or something refreshing.” Then she goes on to advise him to get M. de Boissy to send him ten dozen vipers from Poitou in a case divided into three or four compartments lined with hay and moss, so that they can be kept at their ease. He is to take two every morning. The heads are to be cut off, the bodies to be scalded and cut into small pieces, and used to stuff a fowl. He is to continue this treatment for a month.

The early London Pharmacopœias gave the following form for the Trochisci Viperum required in the preparation of Theriaca: Remove the skin, entrails, head, fat and tail, and boil the flesh of vipers in 8 oz. of water with dill and a little salt, add 2 oz. of white bread twice toasted, ground and sifted, and make into troches, your hands being anointed with opobalsamum or expressed oil of nutmeg. Dry them on a sieve turned bottom upwards in an open place. Turn them frequently until they are quite dry, and keep them in a well-stopped glass or glazed vessel. They will keep good for a year, but it is better to make the treacle with them as soon after they are made as possible.

Quincy (1724) had great confidence in their virtues. He writes, “That they are Balsamic and greatly Restorative is confirm’d by long Experience; for we have many instances in Physical Histories of Persons arriving at a healthful old age by their frequent use, as well as others who recover’d from deplorable Decays and Weaknesses.” Then he proceeds at considerable length to compare the juices of these animals with those of terebinthous plants, which are mostly evergreens. “Moreover they have been experienc’d to do wonders in cutaneous cases; the Force and Activity of their parts breaking thro’ the little obstructions in the Miliary Glands, which turn into Ichor, Scabs, and Blotches” (those old practitioners knew exactly how their remedies acted); “and by restoring a free perspiration render the skin smooth and beautiful”; and much more on cures of itch, leprosy, and the worst skin eruptions.

Viper wine was a very popular tonic. It was believed to cure barrenness in women. An essence of vipers was believed in as an aphrodisiac, but Dr. James (1747) tells us that what was then advertised and sold in London under that name was tincture of cantharides. This author is sceptical about vipers altogether. He had given the flesh, broth, and salt of vipers in large quantities, but had come to the conclusion that the broths and flesh were no better than the broths and flesh of fowl, veal, or mutton, prepared in the same way, and as to the salt, he was sure that the salt of hartshorn or any other animal salt would answer just as well.

The vipers employed for medicine were the common vipers, which in this country are usually called adders (Vipera communis).

A common recipe for viper broth was to boil together a chicken with a middling-sized viper from which the head, skin, and entrails had been removed. These made a quart of good broth.

MUMMIES.

The employment of mummies in medicine does not seem to have been very ancient, nor did it become permanent. Who introduced it is not known. Ephraim Chambers in his Cyclopœdia (1738) says, “Mummy is said to have been first brought into use in medicine by the malice of a Jewish physician, who wrote that flesh thus embalmed was good for the cure of divers diseases, and particularly bruises, to prevent the blood’s gathering and coagulating.” Pomet also says that a Jewish physician had written about the medicinal value of mummy, but he does not suggest that he had recommended it out of malice.

The trade in mummies was evidently in the hands of the Jews and Armenians at the time when Pomet wrote, and, according to him, the fading popularity of mummy as a medicine was the result of the rogueries practised by these Jews. He tells of a Guy de la Fontaine, the King’s physician, who, when visiting in Egypt, went to see a Jew in Alexandria who traded in mummies, and after some difficulty was admitted into the Jew’s warehouse, where he saw several bodies piled one upon another. “After a reflection of a quarter of an hour he asked him what druggs he made use of, and what sort of bodies were fit for his service. The Jew answered that as to the dead he took such bodies as he could get, whether they died of a common disease or of some contagion. As to the druggs, they were nothing but a heap of some old druggs mixed together which he applied to the bodies, which after he had dried in an oven he sent into Europe, and was amazed to see the Christians were lovers of such filthiness.” This very frank Jew must have been on the point of retiring from business.

Pomet regrets that he is not able to stop the abuses of the dealers in this commodity, so he has to content himself with advising those who buy mummy to choose what is of a fine shining black, not full of bones and dirt, and of a good smell. He also tells us it is good for contusions, and to prevent the blood from coagulating in the body (1694).

Ambrose Paré, who wrote before Pomet, was even more suspicious. He mentions that it was held by some that the mummies then in use were made and fashioned in France; that they were bodies stolen at night from the gibbets, the brains and entrails removed, and the bodies dried in a furnace, and then dipped in pitch. Paré states that he never prescribes mummy.

Oswald Crollius seems to have had no objection to artificial mummies. In his “Royal Chemist” he gives a process for preparing one. The carcase of a young man (some say a red-haired young man) who had been killed, that is, did not die of disease, and, it is to be presumed, had not been buried, was to lie in cold water in the air for twenty-four hours. The flesh was to be cut in pieces and sprinkled with myrrh and a little aloes. This was then to be soaked in spirit of wine and turpentine for twenty-four hours, hung up for twelve hours, again soaked in the spirit mixture for twenty-four hours, and finally hung up in a dry place to dry.

Mummies were principally recommended for consumption, wasting of flesh, ulcers, and various corruptions.

Nicasius Le Febre, F.R.S., Professor of Chemistry to Charles II, in his “Compleat Body of Chymistry,” 1670, says the best mummies for medical use were those of bodies dried up in the hot sands of Lybia, where sometimes whole caravans were overwhelmed by simooms and suffocated. “This sudden suffocation doth concentrate the spirits in all the parts by reason of the fear and sudden surprisal which seizes on the travellers.” Next to these Lybian mummies Le Febre recommends the dried corpse of a young lusty man of about 25 to 30 years of age who has been suffocated or hanged. He gives directions for drying the flesh, smoking it for a philosophical month, and then it is to be given in doses of 1 to 3 grains with some old treacle (theriaca) and vipers’ flesh made into an electuary with spirit of wine. It was specially good against pestilential diseases.

DIPPEL’S ANIMAL OIL.

Animal oil, oil of harts’ horns, or empyreumatic oil, as it was variously called, or Dippel’s animal oil, which was the original, was highly prized as a medicine in the eighteenth century, and disputed the palm for nastiness with the balsam of sulphur. Dippel made it from harts’ horns, but later formulas directed it to be made from any bones, from blood, or indeed from any animal substance. In distilling the horn some water first came over, and this was rejected. At the end of the operation the distillate consisted of carbonate of ammonia in solution and an empyreumatic oil, very dark and fœtid. The spirit was drawn off by filtration, and the oil which remained in the filter was rectified by as many as twenty distillations, the residue increasing at each operation and the rectified oil becoming paler. As it became brown by exposure to light it was the practice to put it up in 1 drachm bottles, which were buried in sand.

The virtues of this preparation were highly vaunted. Frederick Hoffmann strongly recommended it, especially when fever threatened. Twenty to thirty drops on a lump of sugar, followed by a glass of wine, were said to procure a calm and refreshing sleep, often continuing for twenty hours. It would be almost shorter to enumerate the complaints it was not recommended for than those which its advocates alleged it would cure. Epilepsy, apoplexy, palsy, plague, pleurisy, leprosy, and all skin diseases down to ringworm, fevers, colds, and headaches of all sorts were said to yield to its virtues.

Johann Conrad Dippel, its inventor and medical sponsor, was a strange, shifty, but clever adventurer. Born in 1673, near Darmstadt, his father, a Lutheran minister, hoped to train his son to his own profession. He was sent when quite a youth to Giessen University, where he distinguished himself and soon became an ardent controversialist. At that time the Protestants in Germany were divided into Orthodox and Pietists, the latter seeking to restore the personal spirituality which they considered the orthodox Lutherans were burying in formalities. Young Dippel argued vigorously on the orthodox side, and went to Strasburg to preach his views. There he also practised alchemy and cheiromancy and, besides, got mixed up in broils and disturbances. His inconsistent life compelled him to leave Strasburg, and having spent some time at Landau, Neustadt, and Worms, he returned to Giessen, where he became as ardent a Pietist as he had previously been an Orthodox. He took his degree, and then, having exhausted his father’s funds, took to travelling, and practised medicine and alchemy, occasionally reverting to theology, but now denouncing Protestantism in all its diversities.

Getting to Berlin, and securing the confidence of some wealthy believers, he established a laboratory where he produced this animal oil and, more important still, in trying to imitate a Florentine lake from cochineal, accidentally produced Prussian blue, but did not realise the value of this discovery. He claimed to have succeeded in making gold, and on the strength of his representations was able to get deeply into debt, purchasing, among other luxuries, a castle and estate for fifty thousand florins. In 1707 he was imprisoned for a short time in Berlin, and when he regained his freedom made his way to Amsterdam. He took a medical degree at Leyden, and was acquiring a good medical practice at Amsterdam when his creditors and religious antagonists compelled him to escape from Holland. He went to Altona and then to Hamburg, but was ordered to leave both these cities. Copenhagen was his next home, and there again he suffered imprisonment. He was sent to the Island of Bornholm, where he practised as a physician until he was freed on the instructions of the Queen of Denmark. His medical reputation must have been both wide and high, for in 1727 the King of Sweden who could not get cured of a malady by his own physicians sent for Dippel, who completely succeeded. His troubled life seemed likely now to be exchanged for peace and prosperity, but this was not to be. The king would willingly have kept Dippel near him, but Sweden was a Protestant nation, and the clergy and people did not forget his scoffing attacks on their cherished faith. They would not have him among them, and Dippel had to return to Germany. After residing for a short time at Lauenburg and Celle, he at last found a refuge at the Castle of Wittgenstein, the owner of which, Count Wittgenstein, was one of his adherents. There he lived from 1729 to 1734. The last event recorded of him was characteristic. It had been announced that he was dead. Dippel published an indignant denial, and declared his assurance that he would not die until the year 1808. The prophecy failed, for the next year, 1734, he was found dead in bed at the castle of Wittgenstein.

The story of his discovery of Prussian blue is curious. When he was in Berlin, an artist, named Diesbach, was preparing some Florentine lake from a combination of alum and cochineal, acted on by sulphate of iron and fixed alkali. He asked Dippel for some of the alkali left over in his retort after he had distilled some of his animal oil. This seemed to spoil the product, for it yielded a blue instead of a crimson lake. Dippel tried it himself and got the same result. But he did not appreciate the value of this product, and it was left for Scheele to trace its chemical history.

SPERMACETI.