MELAMPUS.
Melampus was a shepherd to whom we owe, as legend tells us, hellebore (Gr. Melampodion) and iron as medicines. Melampus studied nature closely, and, when young, brought up by hand some young serpents, who were dutifully grateful for the cares he had bestowed on them. One day, finding him asleep, two of them crept to his ears and so effectively cleaned them with their tongues that when he woke he found he could easily make out the language of birds, and hear a thousand things which had previously been hidden from man. Thus he became a great magician. In tending his goats he observed that whenever they ate the black hellebore they were purged. Afterwards, many of the women of Argos were stricken with a disease which made them mad. They ran about the fields naked, and believed they were cows. Among the women so afflicted were the three daughters of Proetus, the king of Argos. Melampus undertook to cure the three princesses, and did so by giving them the milk of the goats after they had eaten the hellebore. His reward was one of them for his wife and a third of the kingdom. Another cure effected by Melampus was by his treatment of Iphiclus, king of Phylacea, who greatly desired to beget children. Melampus gave him rust of iron in wine, and that remedy proved successful. This was the earliest Vinum Ferri. Melampus is supposed to have lived about 1380 B.C.
GLAUCUS.
Glaucus, son of Minos, king of Crete, was playing when a child and fell into a large vat of honey, in which he was suffocated. The child being lost the king sent for Polyidus of Argos, a famous magician, and ordered him to discover his son. Polyidus having found the dead body in the honey, it occurred to Minos that so clever a man could also bring him back to life. He therefore commanded that the magician should be put into the same vat. While perplexed at the problem before him, Polyidus saw a serpent creeping towards the vat. He seized the beast and killed him. Presently another serpent came, and looked on his dead friend. The second went out of the place for a few minutes and returned with a certain herb which he applied to the dead reptile and soon restored him to life. Polyidus took the hint and used the same herb on Glaucus with an equally satisfactory result. He restored him to his father, who loaded the sorcerer with gifts. Unfortunately in telling the other details of this history the narrator has forgotten to inform us of the name of the herb which possessed such precious properties. Polyidus, according to Pausanias, was a nephew of Melampus.
CHIRON.
Chiron the Centaur was very famous for his knowledge of simples, which he learned on Mount Pelion when hunting with Diana. The Centaury owes its name to him, either because he used it as a remedy or because it was applied to his wound. His great merit was that he taught his knowledge of medicines to Æsculapius, to Hercules, to Achilles, and to various other Greek heroes. In the Iliad Homer represents Eurypylus wounded by an arrow asking Patroclus
With lukewarm water wash the gore away With healing balms the raging smart allay Such as sage Chiron, sire of pharmacy, Once taught Achilles, and Achilles thee. (Il., Bk. XI., Pope’s Translation.)
Chiron was shot in the foot by Hercules by an arrow which had been dipped in the blood of the Hydra of Lerna, and the wound caused intense agony. One fable says that Chiron healed this wound by applying to it the herb which consequently bore the name of Centaury; but the more usual version is that his grief at being immortal was so keen that Hercules induced Jupiter to transfer that immortality to Prometheus, and that Chiron was placed in the sky and forms the constellation of Sagittarius. The Centaurs were a wild race inhabiting Thessaly. Probably they were skilful horse tamers and riders, and from this may have grown the fable of their form.
ACHILLES.
Achilles carried a spear at the siege of Troy which had the benign power of healing the wounds it made. He discovered the virtues of the plant Achillea Milfoil, but Pliny leaves it doubtful whether he cured the wounds of his friend Telephas by that remedy or by verdigris ointment, which he also invented.
ARISTES.
Aristes, king of Arcadia, was another famous pupil of Chiron. He is credited with having introduced the silphion or laser which became a popular medicine and condiment with the ancients, and which was long believed to have been their name for asafœtida, but which modern authors have doubted, alleging that silphion was the product of Thapsia silphion. Aristes is further said to have taught the art of collecting honey and of cultivating the olive.
MEDEA.
Medea of Colchis is one of the most discussed ladies of mythical history. Euripides, Ovid, and other poets represented her for the purposes of their poems as a fiend of inhuman ferocity. Some more trustworthy historians believe that she was a princess who devoted a great deal of study to the medicinal virtues of the plants which grew in her country, and that she exercised her skill on the poor and sick of her country. Certainly the marvellous murders attributed to her must have been planned by a tragic poet to whom no conditions were impossible. Diodorus declares that the Corinthians stoned her and her sons, and afterwards paid Euripides five talents to justify their crime. Medea’s claim to a place in this section is the adopted theory that she discovered the poisonous properties of colchicum, which derived its name from her country. Colchis had the reputation of producing many poisonous plants; hence the Latin expression “venena Colchica.”
MORPHEUS.
Morpheus was, according to the Roman poets, the son or chief minister of the god of sleep (Somnus). The god himself was represented as living in Cimmerian darkness. Morpheus derived his name from Morphe, (Gr., form or shape), from his supposed ability to mimic or assume the form of any individual he desired to pose as in dreams. Thus Ovid relates how he appeared to Alcyone in a dream as her husband, who had been shipwrecked, and narrated to her all the circumstances of the tragedy. Morpheus is represented with a poppy plant in his hand bearing a capsule with which he was supposed to touch those whom he desired to put to sleep. He also had the wings of a butterfly to indicate his lightness. Sertürner adopted the term “morphium” as the name of the opium alkaloid which he had discovered.
PYTHAGORAS.
Pythagoras, who lived in the sixth century before Christ, has been the subject of so many legends that it is difficult to separate the philosopher in him from the charlatan. He is said to have tamed wild beasts with a word, to have visited hell, to have recounted his previous stages of existence from the siege of Troy to his own life, and to have accomplished many miracles. Probably these were the myths which often gather round great men, and it is certain that from him or from his disciples in his name much exact learning, especially in mathematics, has reached us. Pythagoras was famous in many sciences. His chief contribution to pharmacy was the invention of acetum scillae. According to Pliny he wrote a treatise on squills, which he believed possessed magic virtues. Pliny also states that he attributed magic virtues to the cabbage, but it is not certain that he meant the vegetable which we call the cabbage. Aniseed was another of his magic plants. Holding aniseed in the left hand he recommended as a cure for epilepsy, and he prescribed an anisated wine and also mustard to counteract the poisonous effect of the bites of scorpions. An Antidotum Pythagoras is given in some old books, but there is no authority for supposing that this was devised by the philosopher. It was composed of orris, 18 drachms and 2 scruples; gentian, 5 drachms; ginger, 4½ drachms; black pepper, 4 drachms; honey, q.s.
THE PATRON SAINTS OF PHARMACY.
Cosmas and Damien, who are regarded as the patron saints of pharmacy in many Catholic countries, were two brothers, Arabs by birth, but who lived in the city of Egea, in Cilicia, where they practised medicine gratuitously. Overtaken by the Diocletian persecution in the fourth century, they were arrested and confessed their faith. Being condemned to be drowned, it is related that an angel severed their bonds so that they could gain the shore. They were then ordered to be burnt, but the fire attacked their executioners, several of whom were killed. Next they were fastened to a cross and archers shot arrows at them. The arrows, however, were turned from them and struck those who had placed them on the crosses. Finally they were beheaded, and their souls were seen mounting heavenward. For centuries their tomb at Cyrus, in Syria, was a shrine where miracles of healing were performed, and in the sixth century the Emperor Justinian, who believed he had been cured of a serious illness by their intercession, not only beautified and fortified the Syrian city, but also built a beautiful church in their honour at Constantinople. Later, their relics were removed to Rome, and Pope Felix consecrated a church to them there. Physicians and pharmacists throughout Catholic Europe celebrated their memory on September 27th for centuries.
FABLES OF PLANT MEDICINES.
The Mandrake (Atropa Mandragora) has been exceptionally famous in medical history. Its reputation for the cure of sterility is alluded to in the story of Leah and Rachel (Genesis xxx, 14-16). It is not, however, certain that the Hebrew word “dudaim” should be translated mandrake. Various Biblical scholars have questioned this which was the Septuagint rendering. Lilies, violets, truffles, citrons, and other fruits have been suggested. In Cant., vii, 14, the same plant is described as fragrant, and the odour of the mandrake is said to be disagreeable. Mandragora is described in Chinese books of medicine, and from Hippocrates down to almost modern times every writer on the art of healing treats it with reverence. Hippocrates asserts that a small dose in wine, less than would occasion delirium, will relieve the deepest depression and anxiety. The roots of the mandrake are often of a forked shape and were supposed to represent the human form, some being regarded as male and others as female. This fancy originated with Pythagoras, who conferred on the mandrake the name of anthropomorphon. It was said that when the roots were drawn from the earth they gave a human shriek. Shakespeare in Romeo and Juliet alludes to this superstition:
And shrieks like mandrakes torn out of the earth That living mortals hearing them run mad.
In Othello again Shakespeare refers to this medicine, and particularly to its alleged narcotic properties:
Not poppy, nor mandragora, Nor all the drowsy syrups of the world.
In Antony and Cleopatra, too, Cleopatra says, “Give me to drink mandragora” (that she may sleep out the great gap of time while Antony is away); and Banquo in Macbeth, when he asks, “Or have we eaten of the insane root that takes the reason prisoner?” is believed to allude to the mandrake.
There is a good deal of evidence that mandragora was used in ancient and mediæval times not only as a soporific, but also as an anæsthetic. Dioscorides explicitly asserts this property of the root more than once. He describes a decoction of which a cupful is to be taken for severe pains, or “before amputations, or the use of the cautery, to prevent the pain of those operations.” Elsewhere he alludes to its employment in parturition, and in another passage dealing with a wine prepared from the external coat of the root, says, “The person who drinks it falls in a profound sleep, and remains deprived of sense three or four hours. Physicians apply this remedy when the necessity for amputation occurs, or for applying the cautery.” Pliny refers to the narcotic powers of the mandrake, and among later writers its effects are often described. Josephus mentions a plant which he calls Baaras, which cured demoniacs, but could only be procured at great risk, or by employing a dog to uproot it, the dog being killed in the process. This Baaras is supposed to have been mandrake. Dr. Lee in his Hebrew Lexicon quotes from a Persian authority an allusion to a similar root which, taken inwardly, “renders one insensible to the pain of even cutting off a limb.”
Baptista Porta describes the power of the mandrake in inducing deep sleep, and in A. G. Meissner’s “Skizzen,” published at Carlsruhe in 1782, there is a story of Weiss, surgeon to Augustus, King of Poland and Elector of Saxony, who surreptitiously administered a potion (of what medicine is not stated) to his royal master, and during his insensibility cut off a mortifying foot.
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